Cheapest return flights from Madrid to Panama City in December from $834

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in December 2025 (see full year).

Return flights

06 Dec - 13 Dec Iberia direct
20 Dec - 31 Dec Iberia direct
13 Dec - 05 Jan Iberia direct
05 Dec - 14 Dec Air Europa direct
05 Dec - 13 Dec Air Europa direct
08 Dec - 14 Dec Air Europa direct
29 Dec - 05 Jan Iberia direct
29 Dec - 07 Jan Iberia direct
27 Dec - 10 Jan Iberia direct
03 Dec - 13 Dec Air France
27 Dec - 03 Jan Iberia direct
19 Dec - 06 Jan Turkish Airlines
28 Dec - 11 Jan Turkish Airlines
26 Dec - 05 Jan Turkish Airlines
26 Dec - 04 Jan Turkish Airlines
27 Dec - 06 Jan Turkish Airlines
19 Dec - 31 Dec KLM

Also check the deals for one-way flights from Madrid to Panama City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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