Cheapest return flights from Madrid to Panama City in April from $641

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in April 2025 (see full year).

Return flights

26 Apr - 03 May Air France
06 Apr - 27 Apr Air France
27 Apr - 03 May Air France
28 Apr - 04 May Air France
27 Apr - 04 May Air France
21 Apr - 03 May KLM
14 Apr - 03 May KLM
23 Apr - 03 May Air France
17 Apr - 27 Apr Air France
17 Apr - 03 May Air France
11 Apr - 03 May Air France
03 Apr - 17 Apr Iberia direct
21 Apr - 28 Apr Air Europa direct
27 Apr - 04 May Air Europa direct
06 Apr - 27 Apr Air Europa direct
17 Apr - 24 Apr Iberia direct
19 Apr - 28 Apr Iberia direct
14 Apr - 26 Apr Iberia direct
07 Apr - 19 Apr Air France
04 Apr - 12 Apr Air Europa direct

Also check the deals for one-way flights from Madrid to Panama City in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City