Cheapest return flights from Madrid to Panama City in April from $671

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in April 2025 (see full year).

Return flights

10 Apr - 26 Apr Iberia direct
05 Apr - 12 Apr Air Europa direct
16 Apr - 25 Apr Air Europa direct
04 Apr - 14 Apr Air Europa direct
14 Apr - 27 Apr Air Europa direct
19 Apr - 28 Apr Air Europa direct
05 Apr - 19 Apr Air Europa direct
13 Apr - 25 Apr Air Europa direct
21 Apr - 03 May Air Europa direct
18 Apr - 03 May Air Europa direct
30 Apr - 07 May Air Europa direct
25 Apr - 04 May Air Europa direct
25 Apr - 02 May Air Europa direct
18 Apr - 27 Apr Air Europa direct
04 Apr - 20 Apr Air Europa direct
28 Apr - 05 May Iberia
28 Apr - 06 May Iberia
17 Apr - 02 May TAP
28 Apr - 05 May Air Europa direct
28 Apr - 06 May Air Europa direct

Also check the deals for one-way flights from Madrid to Panama City in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City