Cheapest return flights from Madrid to Panama City in May from $587

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in May 2025 (see full year).

Return flights

19 May - 31 May Air France
09 May - 18 May KLM
03 May - 18 May Air France
02 May - 18 May KLM
09 May - 25 May KLM
05 May - 19 May Air France
24 May - 31 May Air France
01 May - 13 May KLM
02 May - 14 May KLM
03 May - 27 May KLM
29 May - 12 Jun Air France
31 May - 15 Jun Air France
24 May - 02 Jun KLM
31 May - 19 Jun Air France
07 May - 04 Jun Air Europa direct
24 May - 07 Jun Air France
24 May - 07 Jun Air Europa direct
23 May - 01 Jun Air France

Also check the deals for one-way flights from Madrid to Panama City in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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