Cheapest return flights from Madrid to Panama City in May from $658

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in May 2025 (see full year).

Return flights

11 May - 26 May United
26 May - 08 Jun KLM
24 May - 08 Jun KLM
13 May - 25 May KLM
20 May - 25 May KLM
18 May - 25 May KLM
19 May - 09 Jun KLM
24 May - 07 Jun KLM
31 May - 07 Jun Air France
27 May - 01 Jun KLM
24 May - 01 Jun KLM
26 May - 07 Jun KLM
26 May - 10 Jun KLM
24 May - 10 Jun KLM
16 May - 27 May KLM
05 May - 26 May United
03 May - 27 May Air France
04 May - 12 May United
12 May - 26 May United
11 May - 25 May KLM

Also check the deals for one-way flights from Madrid to Panama City in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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