Cheapest return flights from Madrid to Santiago in October from $891

Best time to book flights for Madrid (MAD) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in October 2025 (see full year).

Return flights

17 Oct - 02 Nov Iberia
01 Oct - 10 Oct Iberia
22 Oct - 07 Nov Iberia
30 Oct - 28 Nov Iberia
13 Oct - 14 Nov Iberia
03 Oct - 16 Oct Turkish Airlines
03 Oct - 16 Oct Iberia direct
03 Oct - 20 Oct Iberia direct
31 Oct - 15 Nov Iberia direct
24 Oct - 01 Nov Iberia direct
17 Oct - 01 Nov Iberia direct
22 Oct - 05 Nov LATAM Airlines Group direct
17 Oct - 02 Nov Iberia direct
18 Oct - 04 Nov LATAM Airlines Group direct
02 Oct - 16 Oct Turkish Airlines
01 Oct - 08 Oct Iberia direct
01 Oct - 10 Oct Iberia direct
01 Oct - 14 Oct Iberia direct
14 Oct - 24 Oct Turkish Airlines
13 Oct - 22 Oct LATAM Airlines Group direct

Also check the deals for one-way flights from Madrid to Santiago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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