Cheapest return flights from Madrid to Santiago in October from $973

Best time to book flights for Madrid (MAD) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in October 2025 (see full year).

Return flights

14 Oct - 10 Nov Iberia
20 Oct - 27 Oct Iberia
05 Oct - 12 Oct Azul Airlines
09 Oct - 10 Nov Delta
30 Oct - 26 Nov Azul Airlines
04 Oct - 30 Oct Azul Airlines
14 Oct - 28 Oct Azul Airlines
04 Oct - 19 Oct Azul Airlines
07 Oct - 30 Oct Azul Airlines
14 Oct - 30 Oct Azul Airlines
15 Oct - 28 Oct Azul Airlines
21 Oct - 26 Oct Azul Airlines
07 Oct - 23 Oct Azul Airlines
29 Oct - 24 Nov Azul Airlines
21 Oct - 08 Nov Azul Airlines
21 Oct - 07 Nov Azul Airlines
27 Oct - 14 Nov Ryanair
21 Oct - 02 Nov Azul Airlines
15 Oct - 02 Nov Azul Airlines
29 Oct - 05 Nov Azul Airlines

Also check the deals for one-way flights from Madrid to Santiago in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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