Cheapest return flights from Madrid to Santiago in December from $951

Best time to book flights for Madrid (MAD) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in December 2025 (see full year).

Return flights

01 Dec - 12 Dec Iberia
01 Dec - 08 Dec Iberia
04 Dec - 11 Dec Azul Airlines
04 Dec - 11 Dec Iberia direct
05 Dec - 12 Dec LATAM Airlines Group
05 Dec - 14 Dec LATAM Airlines Group
01 Dec - 14 Dec LATAM Airlines Group
01 Dec - 12 Dec Iberia direct
08 Dec - 31 Dec LATAM Airlines Group
01 Dec - 31 Dec LATAM Airlines Group
10 Dec - 30 Jan LATAM Airlines Group
25 Dec - 20 Jan LATAM Airlines Group direct
31 Dec - 20 Jan LATAM Airlines Group
31 Dec - 30 Jan LATAM Airlines Group
24 Dec - 23 Jan LATAM Airlines Group
24 Dec - 26 Jan LATAM Airlines Group
31 Dec - 15 Jan Delta
27 Dec - 17 Jan Iberia
31 Dec - 17 Jan Iberia
22 Dec - 22 Jan LATAM Airlines Group

Also check the deals for one-way flights from Madrid to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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