Cheapest return flights from Madrid to Santiago in September from $836

Best time to book flights for Madrid (MAD) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in September 2025 (see full year).

Return flights

04 Sep - 25 Sep Delta
10 Sep - 25 Sep Delta
11 Sep - 25 Sep Delta
08 Sep - 19 Sep Avianca
15 Sep - 03 Oct Avianca
11 Sep - 24 Sep Avianca
16 Sep - 30 Sep Avianca
15 Sep - 26 Sep Avianca
08 Sep - 21 Sep Avianca
01 Sep - 30 Sep Avianca
03 Sep - 23 Sep Avianca
15 Sep - 04 Oct Avianca
10 Sep - 10 Oct LATAM Airlines Group direct
17 Sep - 08 Oct LATAM Airlines Group
15 Sep - 03 Oct Iberia direct
15 Sep - 02 Oct LATAM Airlines Group
09 Sep - 03 Oct LATAM Airlines Group direct
12 Sep - 17 Oct LATAM Airlines Group
16 Sep - 07 Oct LATAM Airlines Group direct
22 Sep - 22 Oct Ryanair

Also check the deals for one-way flights from Madrid to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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