Cheapest return flights from Madrid to Santiago in September from $816

Best time to book flights for Madrid (MAD) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in September 2025 (see full year).

Return flights

15 Sep - 21 Sep Delta
01 Sep - 21 Sep Delta
08 Sep - 21 Sep Delta
12 Sep - 21 Sep Delta
14 Sep - 12 Oct Delta
17 Sep - 30 Sep Delta
15 Sep - 30 Sep Delta
16 Sep - 30 Sep Delta
14 Sep - 30 Sep Delta
15 Sep - 06 Oct Delta
08 Sep - 11 Oct Iberia
05 Sep - 23 Sep Iberia
03 Sep - 28 Sep Delta
16 Sep - 07 Oct Delta
14 Sep - 18 Oct Azul Airlines
18 Sep - 06 Oct Delta
12 Sep - 03 Oct Air Europa
21 Sep - 03 Oct Azul Airlines
21 Sep - 04 Oct Azul Airlines
14 Sep - 09 Oct LATAM Airlines Group direct

Also check the deals for one-way flights from Madrid to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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