Cheapest return flights from Chicago to Panama City in April from $653

Best time to book flights for Chicago (MDW) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Chicago (MDW) to Panama City (PTY) in April 2025 (see full year).

Return flights

30 Apr - 04 May Delta
13 Apr - 19 Apr LATAM Airlines Group
16 Apr - 22 Apr LATAM Airlines Group
15 Apr - 21 Apr LATAM Airlines Group
10 Apr - 13 Apr Frontier Airlines
22 Apr - 29 Apr Delta
17 Apr - 23 Apr Delta
15 Apr - 25 Apr Delta
07 Apr - 11 Apr Delta

Also check the deals for one-way flights from Chicago to Panama City in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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