Cheapest return flights from Mexico City to Panama City in April from $479

Best time to book flights for Mexico City (MEX) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in April 2025 (see full year).

Return flights

04 Apr - 11 Apr Copa direct
13 Apr - 19 Apr Copa direct
10 Apr - 24 Apr Copa direct
13 Apr - 17 Apr Copa direct

Also check the deals for one-way flights from Mexico City to Panama City in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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