Cheapest return flights from Mexico City to Santiago in May from $454

Best time to book flights for Mexico City (MEX) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in May 2025 (see full year).

Return flights

06 May - 14 May Arajet
06 May - 13 May Arajet
29 May - 11 Jun Arajet
11 May - 28 May Arajet
05 May - 13 May Viva Aerobus
08 May - 22 May Copa
02 May - 08 May Copa
15 May - 28 May Copa
16 May - 21 May Copa
08 May - 21 May Copa
01 May - 13 May Avianca
26 May - 01 Jun Avianca
26 May - 01 Jun LATAM Airlines Group direct

Also check the deals for one-way flights from Mexico City to Santiago in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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