Cheapest return flights from Mexico City to Santiago in September from $610

Best time to book flights for Mexico City (MEX) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in September 2025 (see full year).

Return flights

12 Sep - 21 Sep Avianca
14 Sep - 22 Sep Avianca
12 Sep - 22 Sep Avianca
03 Sep - 17 Sep Avianca
23 Sep - 30 Sep Aeromexico
14 Sep - 22 Sep LATAM Airlines Group direct
12 Sep - 21 Sep LATAM Airlines Group direct
13 Sep - 20 Sep LATAM Airlines Group direct
03 Sep - 17 Sep LATAM Airlines Group direct
23 Sep - 30 Sep LATAM Airlines Group direct

Also check the deals for one-way flights from Mexico City to Santiago in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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