Cheapest return flights from Mexico City to Santiago in September from $602

Best time to book flights for Mexico City (MEX) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in September 2025 (see full year).

Return flights

14 Sep - 05 Oct Arajet
11 Sep - 21 Sep Arajet
23 Sep - 02 Oct LATAM Airlines Group
14 Sep - 28 Sep Copa
15 Sep - 28 Sep Copa
15 Sep - 22 Sep Copa
15 Sep - 05 Oct Copa
12 Sep - 28 Sep LATAM Airlines Group direct
14 Sep - 05 Oct LATAM Airlines Group direct
20 Sep - 27 Sep Volaris
15 Sep - 05 Oct LATAM Airlines Group direct
06 Sep - 13 Sep LATAM Airlines Group
13 Sep - 23 Sep LATAM Airlines Group
15 Sep - 28 Sep LATAM Airlines Group direct
15 Sep - 22 Sep LATAM Airlines Group direct

Also check the deals for one-way flights from Mexico City to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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