Cheapest return flights from Mexico City to Santo Domingo in October from $272

Best time to book flights for Mexico City (MEX) to Santo Domingo (SDQ) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Santo Domingo (SDQ) in October 2025 (see full year).

Return flights

03 Oct - 10 Oct Arajet direct
29 Oct - 03 Nov Arajet direct
18 Oct - 26 Oct Aeromexico direct
18 Oct - 27 Oct Aeromexico direct
12 Oct - 19 Oct Aeromexico direct
15 Oct - 30 Oct Aeromexico direct
20 Oct - 01 Nov Aeromexico direct
21 Oct - 27 Oct Aeromexico direct
13 Oct - 19 Oct Aeromexico direct
28 Oct - 03 Nov Aeromexico direct
09 Oct - 20 Oct Copa
03 Oct - 12 Oct Arajet direct

Also check the deals for one-way flights from Mexico City to Santo Domingo in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santo Domingo

Cheap car rent in Santo Domingo