Cheapest return flights from Mexico City to Santa Cruz in April from $615

Best time to book flights for Mexico City (MEX) to Santa Cruz (VVI) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Santa Cruz (VVI) in April 2025 (see full year).

Return flights

28 Apr - 05 May LATAM Airlines Group
07 Apr - 14 Apr Avianca
14 Apr - 18 Apr Avianca
08 Apr - 05 May Avianca
17 Apr - 27 Apr LATAM Airlines Group
21 Apr - 24 Apr Aeromexico
12 Apr - 19 Apr Aeromexico

Also check the deals for one-way flights from Mexico City to Santa Cruz in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santa Cruz

Cheap car rent in Santa Cruz