Cheapest return flights from Chicago to Prague in May from $632

Best time to book flights for Chicago (ORD) to Prague (PRG) flights at AirHint

AirHint found the following cheapest return flights from Chicago (ORD) to Prague (PRG) in May 2025 (see full year).

Return flights

06 May - 24 May Spirit Airlines
04 May - 14 May Spirit Airlines
05 May - 05 Jun Spirit Airlines
18 May - 25 May SWISS
10 May - 17 May Frontier Airlines
17 May - 24 May Spirit Airlines
04 May - 18 May Spirit Airlines
20 May - 26 May Air Canada
27 May - 04 Jun Spirit Airlines
22 May - 28 May Spirit Airlines
10 May - 26 May Frontier Airlines
18 May - 31 May Spirit Airlines
26 May - 09 Jun Air Canada
19 May - 01 Jun Spirit Airlines
23 May - 06 Jun Air Canada
29 May - 18 Jun Icelandair
30 May - 06 Jun United
26 May - 02 Jun United
28 May - 04 Jun United

Also check the deals for one-way flights from Chicago to Prague in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague