Cheapest return flights from Chicago to Panama City in April from $378

Best time to book flights for Chicago (ORD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Chicago (ORD) to Panama City (PTY) in April 2025 (see full year).

Return flights

09 Apr - 16 Apr Avianca
10 Apr - 17 Apr Avianca
12 Apr - 14 Apr Avianca
25 Apr - 03 May Avianca
18 Apr - 20 Apr Copa direct
04 Apr - 11 Apr Avianca
25 Apr - 03 May Copa direct
11 Apr - 14 Apr Copa direct
10 Apr - 17 Apr Copa direct
12 Apr - 14 Apr Copa direct
09 Apr - 16 Apr Copa direct
04 Apr - 11 Apr Copa direct

Also check the deals for one-way flights from Chicago to Panama City in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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