Cheapest return flights from Palermo to Istanbul in October from $262

Best time to book flights for Palermo (PMO) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (IST) in October 2025 (see full year).

Return flights

20 Oct - 24 Oct ITA Airways
19 Oct - 22 Oct Ryanair
16 Oct - 16 Oct Condor
20 Oct - 24 Oct Turkish Airlines direct
08 Oct - 12 Oct Ryanair
04 Oct - 08 Oct Turkish Airlines direct
19 Oct - 22 Oct Turkish Airlines direct
03 Oct - 08 Oct Turkish Airlines direct
02 Oct - 06 Oct Turkish Airlines direct
08 Oct - 12 Oct Turkish Airlines direct

Also check the deals for one-way flights from Palermo to Istanbul in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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