Cheapest return flights from Palermo to Istanbul in December from $273

Best time to book flights for Palermo (PMO) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (IST) in December 2025 (see full year).

Return flights

12 Dec - 19 Dec Turkish Airlines direct
14 Dec - 19 Dec Turkish Airlines direct
10 Dec - 16 Dec Ryanair
07 Dec - 14 Dec Turkish Airlines direct
07 Dec - 15 Dec Turkish Airlines direct
24 Dec - 26 Dec Turkish Airlines direct
08 Dec - 14 Dec Turkish Airlines direct
11 Dec - 17 Dec Ryanair
24 Dec - 11 Jan Turkish Airlines direct
13 Dec - 18 Dec ITA Airways
08 Dec - 16 Dec Ryanair
26 Dec - 12 Jan Turkish Airlines direct
24 Dec - 07 Jan Turkish Airlines direct
24 Dec - 02 Jan Turkish Airlines direct
24 Dec - 10 Jan Ryanair
29 Dec - 02 Jan Ryanair

Also check the deals for one-way flights from Palermo to Istanbul in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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