AirHint found the following cheapest return flights from Pisa (PSA) to Istanbul (IST) in December 2025 (see full year).

Return flights

11 Dec - 14 Dec	Wizz Air Malta
05 Dec - 07 Dec	Wizz Air Malta
03 Dec - 07 Dec	Wizz Air Malta
07 Dec - 09 Dec	easyJet
13 Dec - 16 Dec	Wizz Air Malta
02 Dec - 05 Dec	Wizz Air Malta
06 Dec - 09 Dec	Wizz Air Malta
05 Dec - 08 Dec	easyJet
06 Dec - 08 Dec	Wizz Air Malta
28 Dec - 01 Jan	Ryanair
27 Dec - 31 Dec	Ryanair
27 Dec - 01 Jan	Ryanair
29 Dec - 03 Jan	Ryanair
22 Dec - 05 Jan	Wizz Air Malta
29 Dec - 02 Jan	Ryanair
30 Dec - 04 Jan	Wizz Air Malta
26 Dec - 02 Jan	Ryanair
30 Dec - 02 Jan	Wizz Air Malta
28 Dec - 04 Jan	Ryanair
27 Dec - 02 Jan	Ryanair

Also check the deals for one-way flights from Pisa to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Pisa to Istanbul in December from $144

Return flights