Cheapest return flights from Panama City to Madrid in May from $688

Best time to book flights for Panama City (PTY) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in May 2025 (see full year).

Return flights

06 May - 17 May Air Europa direct
06 May - 21 May Air Europa direct
05 May - 09 Jun Air Europa direct
03 May - 20 May Air Europa direct
04 May - 24 May Air Europa direct
04 May - 21 May Air Europa direct
12 May - 27 May Air Europa direct
08 May - 24 May Iberia direct
01 May - 10 May Iberia direct
15 May - 31 May Iberia direct
01 May - 15 May Iberia direct
03 May - 04 Jun Air France
03 May - 04 Jun Air Europa direct

Also check the deals for one-way flights from Panama City to Madrid in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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