Cheapest return flights from Rome to Panama City in December from $786

Best time to book flights for Rome (ROM) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Rome (ROM) to Panama City (PTY) in December 2025 (see full year).

Return flights

04 Dec - 11 Dec Air France
03 Dec - 10 Dec KLM
23 Dec - 30 Dec Turkish Airlines
27 Dec - 06 Jan Turkish Airlines
28 Dec - 11 Jan Delta
27 Dec - 07 Jan Turkish Airlines
28 Dec - 07 Jan Turkish Airlines
26 Dec - 10 Jan Turkish Airlines
25 Dec - 05 Jan Turkish Airlines
22 Dec - 01 Jan Turkish Airlines
23 Dec - 06 Jan Turkish Airlines
24 Dec - 05 Jan Turkish Airlines
26 Dec - 05 Jan Turkish Airlines

Also check the deals for one-way flights from Rome to Panama City in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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