Cheapest return flights from San Francisco to Panama City in May from $473

Best time to book flights for San Francisco (SFO) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from San Francisco (SFO) to Panama City (PTY) in May 2025 (see full year).

Return flights

29 May - 04 Jun Avianca
03 May - 10 May Avianca
10 May - 15 May Avianca
23 May - 01 Jun Avianca
22 May - 29 May Avianca
23 May - 01 Jun Copa direct
01 May - 08 May Copa direct
12 May - 28 May Copa direct
29 May - 04 Jun Copa direct
10 May - 15 May Copa direct
04 May - 10 May Copa direct
19 May - 24 May United
19 May - 24 May Copa direct
12 May - 17 May Copa direct

Also check the deals for one-way flights from San Francisco to Panama City in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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