Cheapest return flights from San Francisco to Santiago in April from $651

Best time to book flights for San Francisco (SFO) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from San Francisco (SFO) to Santiago (SCL) in April 2025 (see full year).

Return flights

29 Apr - 06 May Copa
09 Apr - 16 Apr Copa
15 Apr - 29 Apr Copa
17 Apr - 01 May Copa
10 Apr - 14 Apr Delta
06 Apr - 20 Apr Delta
06 Apr - 11 Apr Copa
19 Apr - 27 Apr Copa

Also check the deals for one-way flights from San Francisco to Santiago in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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