Cheapest return flights from Santa Cruz to Panama City in December from $478
AirHint found the following cheapest return flights from Santa Cruz (VVI) to Panama City (PTY) in December 2025 (see full year).
Return flights
| 05 Dec - 14 Dec | Avianca | ||
| 30 Dec - 14 Jan | Avianca | ||
| 01 Dec - 08 Dec | Copa | direct | |
| 05 Dec - 14 Dec | Copa | direct | |
| 30 Dec - 14 Jan | Copa | direct |
Also check the deals for one-way flights from Santa Cruz to Panama City in December.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
