Cheapest one-way flights from Guayaquil to Rio Negro in October from $124

AirHint found the following cheapest one-way flights from Guayaquil (GYE) to Rio Negro (MDE) in October 2025 (see full year).

One-Way flights

27 Oct Copa
27 Oct Avianca direct
22 Oct Avianca direct
23 Oct LATAM Airlines Group
24 Oct Avianca
31 Oct Avianca
24 Oct Avianca direct
31 Oct Avianca direct

Also check the deals for return flights from Guayaquil to Rio Negro in October.

Powered by

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rio Negro

Cheap car rent in Rio Negro

Feel free to contact us with any feedback or request another flight research.