Cheapest one-way flights from Guayaquil to Santiago in April from $226

Best time to book flights for Guayaquil (GYE) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Guayaquil (GYE) to Santiago (SCL) in April 2025 (see full year).

One-Way flights

19 Apr Copa
16 Apr Copa
28 Apr Copa
23 Apr Copa
20 Apr Copa
18 Apr Copa
11 Apr Copa
15 Apr Copa
13 Apr Copa
10 Apr Copa

Also check the deals for return flights from Guayaquil to Santiago in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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