Cheapest return flights from Guayaquil to Santiago in April from $461

Best time to book flights for Guayaquil (GYE) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Guayaquil (GYE) to Santiago (SCL) in April 2025 (see full year).

Return flights

10 Apr - 14 Apr Copa
15 Apr - 16 Apr Copa
23 Apr - 12 May Copa
24 Apr - 27 Apr Copa
17 Apr - 24 Apr Copa
17 Apr - 30 Apr Copa
23 Apr - 30 Apr Copa
21 Apr - 12 May Copa
22 Apr - 14 May Copa
19 Apr - 26 Apr Copa
28 Apr - 05 May Copa
19 Apr - 19 May Copa
17 Apr - 21 Apr Copa
18 Apr - 23 Apr LATAM Airlines Group
14 Apr - 21 Apr LATAM Airlines Group
28 Apr - 12 May Copa
14 Apr - 11 May LATAM Airlines Group
21 Apr - 11 May Copa
22 Apr - 12 May Copa
28 Apr - 02 May LATAM Airlines Group

Also check the deals for one-way flights from Guayaquil to Santiago in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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