Cheapest one-way flights from Istanbul to San Francisco in April from $345
AirHint found the following cheapest one-way flights from Istanbul (IST) to San Francisco (SFO) in April 2025 (see full year).
One-Way flights
Also check the deals for return flights from Istanbul to San Francisco in April.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
