Cheapest return flights from Istanbul to San Francisco in April from $454

Best time to book flights for Istanbul (IST) to San Francisco (SFO) flights at AirHint

AirHint found the following cheapest return flights from Istanbul (IST) to San Francisco (SFO) in April 2025 (see full year).

Return flights

01 Apr - 30 Apr KLM
03 Apr - 14 Apr KLM
01 Apr - 01 May British Airways
22 Apr - 27 Apr British Airways
23 Apr - 30 Apr KLM
01 Apr - 08 Apr KLM
02 Apr - 10 Apr KLM
15 Apr - 30 Apr Delta
01 Apr - 20 Apr Lufthansa
14 Apr - 28 Apr Delta
23 Apr - 27 Apr Delta
01 Apr - 01 May Turkish Airlines direct
21 Apr - 03 May Turkish Airlines direct

Also check the deals for one-way flights from Istanbul to San Francisco in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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