Cheapest one-way flights from Madrid to Prague in September from $61

Best time to book flights for Madrid (MAD) to Prague (PRG) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Prague (PRG) in September 2025 (see full year).

One-Way flights

04 Sep Wizz Air Malta
01 Sep Wizz Air Malta
13 Sep Wizz Air Malta
12 Sep Wizz Air Malta
23 Sep Ryanair
04 Sep Ryanair direct
06 Sep Ryanair direct
05 Sep Wizz Air Malta
13 Sep Ryanair direct
23 Sep Ryanair direct

Also check the deals for return flights from Madrid to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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