Cheapest return flights from Madrid to Prague in September from $124

Best time to book flights for Madrid (MAD) to Prague (PRG) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Prague (PRG) in September 2025 (see full year).

Return flights

08 Sep - 13 Sep Wizz Air Malta
01 Sep - 07 Sep Wizz Air Malta
02 Sep - 06 Sep Wizz Air Malta
16 Sep - 19 Sep Ryanair
05 Sep - 07 Sep Wizz Air Malta
05 Sep - 08 Sep Wizz Air Malta
09 Sep - 12 Sep Wizz Air Malta
10 Sep - 13 Sep Ryanair
11 Sep - 13 Sep Wizz Air Malta
20 Sep - 08 Oct Ryanair direct
10 Sep - 14 Sep Ryanair
21 Sep - 08 Oct Vueling Airlines
20 Sep - 10 Oct Ryanair
20 Sep - 11 Oct Ryanair direct
21 Sep - 10 Oct Vueling Airlines
21 Sep - 11 Oct Vueling Airlines

Also check the deals for one-way flights from Madrid to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague