Cheapest one-way flights from Palermo to Istanbul in September from $123

Best time to book flights for Palermo (PMO) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest one-way flights from Palermo (PMO) to Istanbul (IST) in September 2025 (see full year).

One-Way flights

15 Sep Ryanair
08 Sep Ryanair
22 Sep Ryanair
28 Sep Ryanair
11 Sep Ryanair
22 Sep Turkish Airlines direct
28 Sep Turkish Airlines direct
11 Sep Turkish Airlines direct
15 Sep Turkish Airlines direct

Also check the deals for return flights from Palermo to Istanbul in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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