Cheapest return flights from Palermo to Istanbul in September from $242

Best time to book flights for Palermo (PMO) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (IST) in September 2025 (see full year).

Return flights

24 Sep - 27 Sep Air Serbia
17 Sep - 20 Sep Air Serbia
17 Sep - 25 Sep Ryanair
25 Sep - 13 Oct easyJet
16 Sep - 20 Sep Ryanair
16 Sep - 19 Sep Ryanair
25 Sep - 12 Oct easyJet
10 Sep - 17 Sep easyJet
17 Sep - 22 Sep Ryanair
11 Sep - 17 Sep Ryanair
24 Sep - 27 Sep Turkish Airlines direct
05 Sep - 10 Sep Volotea
25 Sep - 12 Oct Turkish Airlines direct
25 Sep - 11 Oct Turkish Airlines direct
25 Sep - 13 Oct Turkish Airlines direct

Also check the deals for one-way flights from Palermo to Istanbul in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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