Cheapest return flights from Palermo to Istanbul in September from $226

Best time to book flights for Palermo (PMO) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (IST) in September 2025 (see full year).

Return flights

13 Sep - 18 Sep Aegean Airlines
17 Sep - 20 Sep Air Serbia
16 Sep - 19 Sep Ryanair
15 Sep - 21 Sep Ryanair
15 Sep - 19 Sep Ryanair
18 Sep - 21 Sep Ryanair
13 Sep - 18 Sep Turkish Airlines direct
24 Sep - 28 Sep Ryanair
07 Sep - 14 Sep Ryanair
19 Sep - 24 Sep easyJet

Also check the deals for one-way flights from Palermo to Istanbul in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul