Cheapest return flights from Madrid to Panama City in October from $697

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in October 2025 (see full year).

Return flights

31 Oct - 10 Nov Air Europa direct
31 Oct - 15 Nov Air Europa direct
31 Oct - 08 Nov Air Europa direct
12 Oct - 18 Oct Air Europa direct
04 Oct - 27 Oct Air France
14 Oct - 23 Oct Air France
25 Oct - 09 Nov KLM
13 Oct - 25 Oct Air Europa direct
08 Oct - 20 Oct Air Europa direct
03 Oct - 13 Oct Air France
03 Oct - 24 Oct Air France
03 Oct - 19 Oct Air France
01 Oct - 10 Oct Air France
01 Oct - 13 Oct Air France
20 Oct - 03 Nov Iberia direct
30 Oct - 09 Nov Delta
18 Oct - 01 Nov Air Europa direct

Also check the deals for one-way flights from Madrid to Panama City in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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