Cheapest return flights from Madrid to San Francisco in October from $531

Best time to book flights for Madrid (MAD) to San Francisco (SFO) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to San Francisco (SFO) in October 2025 (see full year).

Return flights

22 Oct - 12 Nov TAP
20 Oct - 12 Nov TAP
01 Oct - 14 Oct Scandinavian Airlines
10 Oct - 15 Oct Scandinavian Airlines
24 Oct - 03 Nov Lufthansa
28 Oct - 09 Nov Lufthansa
31 Oct - 08 Nov Lufthansa
09 Oct - 25 Oct Lufthansa
01 Oct - 11 Oct TAP
08 Oct - 14 Oct United
02 Oct - 14 Oct Delta
01 Oct - 19 Oct Delta
09 Oct - 16 Oct Delta
01 Oct - 29 Oct Delta
10 Oct - 17 Oct Delta

Also check the deals for one-way flights from Madrid to San Francisco in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in San Francisco

Cheap car rent in San Francisco