Cheapest return flights from Mexico City to Panama City in May from $387

Best time to book flights for Mexico City (MEX) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in May 2025 (see full year).

Return flights

07 May - 14 May Avianca
08 May - 15 May Avianca
27 May - 03 Jun Avianca
08 May - 11 May Copa direct
04 May - 09 May Copa direct
17 May - 19 May Copa direct
15 May - 19 May Copa direct
02 May - 31 May Copa direct
07 May - 14 May Copa direct
19 May - 27 May Copa direct
07 May - 27 May Copa direct
27 May - 03 Jun Copa direct

Also check the deals for one-way flights from Mexico City to Panama City in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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