Cheapest return flights from Prague to Madrid in September from $139

Best time to book flights for Prague (PRG) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest return flights from Prague (PRG) to Madrid (MAD) in September 2025 (see full year).

Return flights

19 Sep - 23 Sep Wizz Air Malta
14 Sep - 16 Sep Ryanair
10 Sep - 13 Sep Ryanair direct
06 Sep - 10 Sep Ryanair direct
06 Sep - 09 Sep Ryanair direct
14 Sep - 20 Sep Ryanair
06 Sep - 13 Sep Ryanair direct
10 Sep - 24 Sep Ryanair direct
10 Sep - 20 Sep Ryanair direct
10 Sep - 23 Sep Ryanair direct
13 Sep - 03 Oct Ryanair
13 Sep - 01 Oct Ryanair direct
13 Sep - 02 Oct Ryanair direct
16 Sep - 03 Oct Ryanair
16 Sep - 01 Oct Ryanair direct
16 Sep - 02 Oct Ryanair direct

Also check the deals for one-way flights from Prague to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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