Cheapest return flights from Panama City to Madrid in November from $723

Best time to book flights for Panama City (PTY) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in November 2025 (see full year).

Return flights

08 Nov - 14 Nov Air Europa direct
01 Nov - 16 Nov Avianca
14 Nov - 01 Dec Air Europa direct
29 Nov - 13 Dec Iberia direct
21 Nov - 03 Dec Air France
04 Nov - 11 Nov Air France
04 Nov - 11 Nov Air Europa direct
25 Nov - 08 Dec United
21 Nov - 01 Dec Air Europa direct
02 Nov - 16 Nov Air France
13 Nov - 30 Nov Air France
01 Nov - 16 Nov Air Europa direct
02 Nov - 16 Nov Air Europa direct

Also check the deals for one-way flights from Panama City to Madrid in November.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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